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WHAT'S NEW  ::  Career Opportunities

Career Opportunities

January 13, 2022
Graduate Student (MSc/MASc or PhD) in Metabolic Models of Rhizobia

Employer: Labs of Dr. George diCenzo and Dr. Laurence Yang, Queen’s University
Location: Kingston, ON, Canada
Closing Date: February 25, 2022

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Job Description

Application Deadline: 31 January 2022

The rhizobia are a diverse group of soil bacteria that fix nitrogen gas to ammonia during endosymbiotic relationships with legumes. Rhizobium inoculants are used in agricultural settings as a replacement for oil-based nitrogen fertilizers and have the potential to fulfill the entire nitrogen requirement of a plant. However, several inter-linked challenges currently prevent us from realizing the full benefits of rhizobium inoculants. Metabolism underpins the ability of rhizobia to survive in soil, compete for interaction with legumes, as well as to fix nitrogen during the symbiosis. Thus, to develop elite rhizobium inoculants, it is crucial to understand rhizobium metabolism and develop models of metabolism that can predict the impacts of genetic engineering.

To this end, we propose to develop a metabolism and macromolecular expression (ME) model of the model rhizobium Sinorhizobium meliloti. This will build upon our recent work modelling the metabolism of S. meliloti (diCenzo et al 2016, diCenzo et al 2018, diCenzo et al 2020) using computational pipelines that we have pioneered (Yang et al 2016, Lloyd et al. 2018, Yang et al 2019). We are recruiting a graduate student (at the MSc/MASc or PhD level) to contribute to this research program. This exciting project will be primarily computational in nature although opportunities for wetlab microbiology experience will be available.

Anticipated Start Date and Duration of Program: The preferred start date is 1 September 2022. The MSc/MASc program at Queen’s University is generally expected to take 2 years. The PhD program at Queen’s University is generally expected to take 4 years.

Required Qualifications: Applicants should hold (or be in the final year of) a BSc or equivalent degree in microbiology, chemical engineering, bioengineering, biochemistry, computational biology, biology, or a related field. Experience with the programming language Python is required. Experience with cell metabolism, bacterial genomes, and mathematical optimization (e.g., linear programming) is preferred but not required as the successful applicant will be trained in these skills. Applicants should also have good communication skills and an interest in collaborating across scientific disciplines.

Application Instructions

Application Instructions: Applicants should submit (1) a cover letter, outlining their qualifications and motivations for this position, (2) a curriculum vitae, (3) unofficial or official university transcripts , and (4) the names and contact information of two references to george.dicenzo@queensu.ca. The application deadline is 31 January 2022. Inquires about the project and position can be requested from Dr. George diCenzo (george.dicenzo@queensu.ca) or Dr. Laurence Yang (laurence.yang@queensu.ca).

Employment Equity: Queen’s University invites applications from all qualified individuals. We are committed to employment equity and diversity in the workplace and welcome applications from women, visible minorities, Aboriginal peoples, persons with disabilities, and LGBTQ2+ persons. We have a track record of supporting all our employees, including our Accommodation in the Workplace Policy, and will provide support in recruitment processes for applicants with accessibility needs. If you require accommodation during the application process, please contact Dr. George diCenzo (george.dicenzo@queensu.ca) or Dr. Laurence Yang (laurence.yang@queensu.ca).

Application Contacts

Dr. George diCenzo


Dr. Laurence Yang


Related Documents

Adobe PDFGraduate Student (MSc/MASc or PhD) in Metabolic Models of Rhizobia

Related Links


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