CSM Member Directory

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Ms. Katrina L Madden

Degree(s): MSc, Bsc

Job Title: PhD Candidate

Department: Biochemistry, Microbiology ad Immunology

Institution: University of Ottawa
94 Riverdale Ave.
Ottawa, Ontario K1S1R2

Contact Information

Email: kmadd079@uottawa.ca
Work Phone: 7057746205
Mobile Phone:

Personal Website:

Research Profile

Section Affiliation: Infections and Immunity

Research Interest:

Epigenetic mechanisms regulate key host immune responses during Mycobacterium tuberculosis (Mtb) infection. However, changes in genome-wide chromatin accessibility in Mtb-infected macrophages remains unknown. Using combinatorial chromatin accessibility (ATAC-seq) and transcriptomics (RNA-seq) profiling, we demonstrate that Mtb infection induces global chromatin remodeling consistent with changes in gene expression signatures.

Keywords: Tuberculosis